Comments on: "Role of individual ionic current systems in ventricular cells hypothesized by a model study" by Matsuoka S, Sarai N, Kuratomi S, Ono K, and Noma A. Jpn J Physiol 53: 105-123, 2003.

نویسندگان

  • Thomas O'Hara
  • Keith Decker
  • Gregory Faber
  • Leonid Livshitz
  • Jonathan Silva
  • Yoram Rudy
چکیده

In a recent article in the Jpn J Physiol Matsuoka et al. [1] present in their discussion section a comparison of their cardiac action potential model and the Luo-Rudy dynamic (LRd) model [2]. Figure 10 in their paper compares the action potential (AP), calcium transient (CaT) and selected ionic currents during the AP. Several results of their LRd simulations are conducted using parameters/protocols that influence the comparison and are not provided in their paper. We repeated all simulations presented in their paper and provide relevant results and discussion in this Letter to the Editor.

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عنوان ژورنال:
  • The Japanese journal of physiology

دوره 54 5  شماره 

صفحات  -

تاریخ انتشار 2004